The findings.

The findings, published this week in The Journal of Neuroscience, may lead to more streamlined therapies for a number of acute and persistent neurological disorders, including glaucoma and retinal artery occlusion . In lots of neurodegenerative diseases, a main element that kills neurons is usually excessive degrees of glutamate, the most abundant excitatory neurotransmitter in lots of parts of the central nervous system . For a long time, the main description for the toxic effects of glutamate is certainly that it overexcites neuronal cells via activation of glutamate receptors and thus kills them. Adriana Di Polo, neuroscientist at the UdeM. Through careful experimentation we now understand that glutamate activates signaling pathways in glial cells that then lead to neuronal loss of life.

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