Those ladies who experienced weaker circadian rhythm activity, lower degrees of activity, or whose peak degree of activity was in the day later, were at highest threat of developing dementia or MCI. This was not a little difference, but a rather sizable, statistically significant one, says Tranah. Those who had the later wake times, whose activity was later in the day, were 80 % more likely to build up MCI or dementia in comparison to females who had previously wake times and earlier activity. Related StoriesResearchers find that stem cell treatment may reduce cognitive impairment related to dementia with Lewy bodiesSpecial orchestra boosts mood and confidence in patients with dementiaLewy Body Composite Risk Score detects LBD and Parkinson's disease dementia in 3 minutesCircadian rhythms play a significant function in the control of sleep-wake cycles and there is considerable proof to show they also are likely involved in regulating certain human brain functions, such as alertness, memory and learning.Cortisol is created primarily by the adrenal cortex . Cortisol is named the tension hormone because it’s secreted in larger amounts within the body’s response to physical or psychological stress. Cortisol amounts normally vary during the day. They’re highest each morning, before waking up just, and lowest during the night. Some social people, however, can’t help to make enough cortisol because they absence an enzyme in the adrenal glands that’s required to create it.