Several lines of evidence support the conclusion that to contribute Hepcidin authors as anti-inflammatory agent, including the observation that hepcidin modulates the expression of genes In addition, in mice induces and that hepcidin pretreatment protected mice from a lethal dose of LPS prinflammatory mediator. In addition, the authors suggest that the persistence of high hepcidin, which are associated with chronic inflammatory diseases and anemia anemia and iron levels could endanger reduce reduce inflammatory reactions in these patients.
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