Citation:* Product: Gail MH

###Citation:* Product: Gail MH. Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk . J Natl Cancer Inst 2008; 100:1037-1041* Editorial: Pepe MS, Janes HE. Gauging the performance of SNPs, biomarkers and clinical factors for predicting risk of breast cancer. J Natl Cancer Inst 2008; 100: 978-979.

In the current study, Mitchell Gail, National Cancer Institute in Bethesda, compared the discriminatory accuracy of these seven SNPs to an established risk model, called the Breast Cancer Risk Assessment Tool . BCRAT uses a woman’s age, age at menarche and at birth of first child, family history of breast cancer cancer and breast biopsy results to predict their risk of disease. He also tested whether the addition of the SNPs to the existing model could improve the accuracy.

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Roswell Park scientists that new combination of medication to colorectal cancer patients which should intolerant or resistant to compared default therapy have. Marwan Fakih, Department of Medicine at Roswell Park Cancer Institute present the results of of a Phase I clinical trial in the American Society of Clinical Oncology 2009 Annual Meeting of, May – 2nd Orlando Orlando.

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