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The study centered on the alpha-5 GABA type A receptors, which will be the principal target for some anesthetics. Prior studies had also suggested that a role is played by these receptors in certain types of anesthesia-related memory impairment. The experiments included genetically built mice that lacked the alpha-5 GABA type A receptors. Behavioral tests were utilized to assess specific types of memory space function. But in mice without A receptors become typed by the alpha-5 GABA, memory space function was unaffected. The memory space deficits were particular to short-term memory, but did not affect working storage.